Methylprednisolone during pregnancy and lactation

Tab Methylprednisolone during pregnancy and lactation, Methylprednisolone category by FDA, its use during pregnancy and lactation its teratogenic effects are described

Pregnancy    Category  C     ( by FDA )

                         Category  C     (AU TGA) (acetate suspension)

                         Category  A    ( AU TGA )

Drug crosses placenta, teratogenic effects in animal studies – Cleft palate, low birth weight, adrenal cortex suppression.

Breast feeding  Corticosteroids are excreted into human milk in small amounts, its presence in breast milk could suppress growth, interfere with endogenous corticosteroid production, or cause other unwanted effects in breast fed babies