Phenobarbital during pregnancy and lactation

Phenobarbitalduring pregnancy and lactation, Phenobarbital category by FDA, its use during pregnancy and lactation its teratogenic effects are described.

Small amount of drug excrete into breast milk, if required low dose should be prescribed.

Phenobarbital during pregnancy and lactation
Pregnancy	Category D       ( by FDA ) Category D        (AU TGA)
	Phenobarbital This drug crosses the placental barrier and distributes in fetal tissues, including the placenta, liver, and brain. Use during the first and third trimesters may be associated with an increased risk of teratogenicity and withdrawal symptoms in the newborn, respectively.
Breast feeding	Phenobarbital excreted into breast milk, watch for sedation, weight gain, and developmental milestones.