Doxycycline during pregnancy and lactation

Doxycycline is generally not recommended during pregnancy or lactation due to potential risks to the developing fetus and infant. It is classified as Pregnancy Category D by the FDA, which means there is evidence of fetal risk based on human data, but the potential benefits from the use of the drug in pregnant women may be acceptable despite the risks.

Pregnancy     Category D       ( by FDA )

                       Category  D       (AU TGA )

1. Pregnancy:

   • Doxycycline is generally contraindicated during pregnancy, especially during the second and third trimesters. The use of doxycycline during pregnancy can lead to permanent discoloration of teeth and reversible inhibition of bone growth in the developing fetus.
   • If a pregnant woman requires treatment with an antibiotic, alternative antibiotics that are safer during pregnancy should be considered. It's essential to discuss the risks and benefits with a healthcare provider.
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2. Lactation:

   • Doxycycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Therefore, it's generally recommended to avoid using doxycycline while breastfeeding, especially in infants and young children.