Propranolol use during pregnancy and lactation

 The use of propranolol during pregnancy requires careful consideration. Some studies have suggested a possible association between propranolol use during pregnancy and an increased risk of fetal growth restriction, low birth weight, and other adverse outcomes. Additionally, propranolol can cross the placenta and may affect the cardiovascular system of the developing fetus, potentially leading to bradycardia (slow heart rate) or hypotension (low blood pressure) in the fetus.

Propranolol is excreted into breast milk, although the amount transferred to the infant is generally low. There have been reports of infants experiencing side effects such as bradycardia, hypoglycemia (low blood sugar), and respiratory depression when breastfed by mothers taking propranolol.

Pregnancy     Category C       ( by FDA )

                       Category  D       (AU TGA )